Novel Anticancer Agents
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Azatoxin, a hybrid of etoposide and ellipticine, originally proposed in the early 1990s, is back in the news as a more favorable cytotoxic alternative acting as a topoisomerase II inhibitor and a spindle poison. Certain azatoxin derivatives are 100 times more active than etoposide.
http://www.thefederalregister.com/d.p/2009-04-23-E9-9344
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